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Yagolovich AV, Kuskov AN, Kulikov PP, Bagrov DV, Petrova PA, Kukovyakina EV, Isakova AA, Khan II, Pokrovsky VS, Nosyrev AE, Stamati PC, Markvicheva EA, Gasparian ME, Spandidos DA, Tsatsakis AM. Assessment of the effects of amphiphilic poly (N‑vinylpyrrolidone) nanoparticles loaded with bortezomib on glioblastoma cell lines and zebrafish embryos. Biomedical Reports, 2024, 20(3), 1-9

Luss AL, Bagrov DV, Yagolovich AV, Kukovyakina EV, Khan II, Pokrovsky VS, Shestovskaya MV, Gasparian ME, Dolgikh DA, Kuskov AN. Toxicity Evaluation and Controlled-Release of Curcumin-Loaded Amphiphilic Poly-N-vinylpyrrolidone Nanoparticles: In Vitro and In Vivo Models. Pharmaceutics. 2024; 16(1):8

Kuznetsova JV, Tkachenko VT, Petrovskaya LM, Filkina ME, Shybanov DE, Grishin YK, Roznyatovsky VA, Tafeenko VA, Pestretsova AS, Yakovleva VA, Pokrovsky VS, Kukushkin ME, Beloglazkina EK. [3+2]-Cycloaddition of Nitrile Imines to Parabanic Acid Derivatives—An Approach to Novel Spiroimidazolidinediones. International Journal of Molecular Sciences. 2024; 25(1):18

Brezgin S, Parodi A, Kostyusheva A, Ponomareva N, Lukashev A, Sokolova D, Pokrovsky VS, Slatinskaya O, Maksimov G, Zamyatnin AA Jr, Chulanov V, Kostyushev D. Technological aspects of manufacturing and analytical control of biological nanoparticles. Biotechnol Adv. 2023 May-Jun;64:108122

Pokrovsky VS, Ivanova-Radkevich VI, Kuznetsova OM. Sphingolipid Metabolism in Tumor Cells. Biochemistry (Mosc). 2023 Jul;88(7):847-866

Pokrovsky VS, Qoura LA, Demidova EA, Han Q, Hoffman RM. Targeting Methionine Addiction of Cancer Cells with Methioninase. Biochemistry (Mosc). 2023 Jul;88(7):944-952

Karshieva SS, Babayeva G, Pokrovsky VS, Shlyapnikov YM, Shlyapnikova EA, Bugrova AE, Kononikhin AS, Nikolaev EN, Kanev IL. Antitumor Effect of Bleomycin Nanoaerosol in Murine Carcinoma Model. Molecules. 2023 May 18;28(10):4157

Shmakova A, Lomov N, Viushkov V, Tsfasman T, Kozhevnikova Y, Sokolova D, Pokrovsky V, Syrkina M, Germini D, Rubtsov M, Vassetzky Y. Cell models with inducible oncogenic translocations allow to evaluate the potential of drugs to favor secondary translocations. Cancer Commun (Lond). 2023 Jan;43(1):154-158

Kosobokova EN, Kalinina NA, Baryshnikova MA, Pokrovsky VS, Solopova ON, Bogush TA, Kosorukov VS. Bioresource collections: algorithms for development and functioning; basic and applied significance. Cardiovascular Therapy and Prevention, 2023. 22(11), 3654

Kalinina EV, Gavriliuk LA, Pokrovsky VS. Oxidative Stress and Redox-Dependent Signaling in Prostate Cancer. Biochemistry (Mosc). 2022 May;87(5):413-424

Machulkin AE, Nimenko EA, Zyk NU, Uspenskaia AA, Smirnova GB, Khan II, Pokrovsky VS, Vaneev AN, Timoshenko RV, Mamed-Nabizade VV, et al. Synthesis and Preclinical Evaluation of Small-Molecule Prostate-Specific Membrane Antigen-Targeted Abiraterone Conjugate. Molecules. 2022; 27(24):8795

Machulkin AE, Uspenskaya AA, Zyk NY, Nimenko EA, Ber AP, Petrov SA, Shafikov RR, Skvortsov DA, Smirnova GB, Borisova YA, Pokrovsky VS, Kolmogorov VS, Vaneev AN, Ivanenkov YA, Khudyakov AD, Kovalev SV, Erofeev AS, Gorelkin PV, Beloglazkina EK, Zyk NV, Khazanova ES, Majouga AG. PSMA-targeted small-molecule docetaxel conjugate: Synthesis and preclinical evaluation. Eur J Med Chem. 2022;227:113936

Morozova E, Abo Qoura L, Anufrieva N, Koval V, Lesnova E, Kushch A, Kulikova V, Revtovich S, Pokrovsky VS, Demidkina T. Daidzein-directed methionine γ-lyase in enzyme prodrug therapy against breast cancer. Biochimie. 2022;201:177-183

Khan II, Karshieva SS, Sokolova DV, Spirina TS, Zolottsev VA, Latysheva AS, Anisimova NY, Komarova MV, Yakunina MN, Nitetskaya TA, Misharin AY, Pokrovsky VS. Antiproliferative, proapoptotic, and tumor-suppressing effects of the novel anticancer agent alsevirone in prostate cancer cells and xenografts. Arch Pharm (Weinheim). 2022 Jan;355(1):e2100316

Abo Qoura L, Morozova E, Kulikova V, Karshieva S, Sokolova D, Koval V, Revtovich S, Demidkina T, Pokrovsky VS. Methionine γ-Lyase-Daidzein in Combination with S-Propyl-L-cysteine Sulfoxide as a Targeted Prodrug Enzyme System for Malignant Solid Tumor Xenografts. Int J Mol Sci. 2022 Oct 10;23(19):12048

Tereshkina YA, Kostryukova LV, Tikhonova EG, Khudoklinova YY, Orlova NA, Gisina AM, Morozevich GE, Melnikov PA, Pokrovsky VS. Chlorin e6 Phospholipid Delivery System Featuring APN/CD13 Targeting Peptides: Cell Death Pathways, Cell Localization, In Vivo Biodistribution. Pharmaceutics. 2022 Oct 18;14(10):2224

Bychkova AV, Yakunina MN, Lopukhova MV, Degtyarev YN, Motyakin MV, Pokrovsky VS, Kovarski AL, Gorobets MG, Retivov VM, Khachatryan DS. Albumin-Functionalized Iron Oxide Nanoparticles for Theranostics: Engineering and Long-Term In Situ Imaging. Pharmaceutics. 2022 Dec 11;14(12):2771

Pokrovskaya MV, Pokrovsky VS, Aleksandrova SS, Sokolov NN, Zhdanov DD. Molecular Analysis of L-Asparaginases for Clarification of the Mechanism of Action and Optimization of Pharmacological Functions. Pharmaceutics. 2022 Mar 9;14(3):599

Xu J, Li JQ, Chen QL, Shestakova EA, Misyurin VA, Pokrovsky VS, Tchevkina EM, Chen HB, Song H, Zhang JY. Advances in Research on the Effects and Mechanisms of Chemokines and Their Receptors in Cancer. Front Pharmacol. 2022 Jun 13;13:920779

Rudzinska-Radecka M, Frolova AS, Balakireva AV, Gorokhovets NV, Pokrovsky VS, Sokolova DV, Korolev DO, Potoldykova NV, Vinarov AZ, Parodi A, Zamyatnin AA Jr. In Silico, In Vitro, and Clinical Investigations of Cathepsin B and Stefin A mRNA Expression and a Correlation Analysis in Kidney Cancer. Cells. 2022 Apr 25;11(9):1455

Suleimanov A, Saduakassova A, Vinnikov D, Pokrovsky V, Mamyrbekova S, Daniyarova A, Kozhabek L. Predictive value of 18F-fluorodeoxyglucose accumulation in visceral fat activity to detect colorectal cancer metastases (prospective observational cohort study). F1000Res. 2022 Oct 10;11:1158.

Zolottsev VA, Latysheva AS, Khan II, Pokrovsky VS, Misharin AY, Design and Synthesis of New Agents for Prostate Cancer Treatment Inspired by Steroidal CYP17 A1 Inhibitors. ChemistrySelect 2022, 7, e202203393

Pokrovsky VS, Abo Qoura L, Morozova E, Bunik VI. Predictive markers for efficiency of the amino-acid deprivation therapies in cancer. Front Med (Lausanne). 2022 Nov 3;9:1035356

Pokrovsky VS, Lukashev AN, Babayeva G, Karshieva SS, Arinbasarova AY, Medentzev AG, Komarova MV, Lukasheva EV. Plasma pharmacokinetics and tissue distribution of L-lysine α-oxidase from Trichoderma cf. aureoviride RIFAI VKM F- 4268D in mice. Amino Acids. 2021 Jan;53(1):111-118

Upadhyay N, Tilekar K, Loiodice F, Anisimova NY, Spirina TS, Sokolova DV, Smirnova GB, Choe JY, Meyer-Almes FJ, Pokrovsky VS, Lavecchia A, Ramaa CS. Pharmacophore hybridization approach to discover novel pyrazoline-based hydantoin analogs with anti-tumor efficacy. Bioorg Chem. 2021 Feb;107:104527

Zolottsev VA, Latysheva АS, Pokrovsky VS, Khan II, Misharin AY. Promising applications of steroid сonjugates for cancer research and treatment. Eur J Med Chem. 2021 Jan 15;210:113089

Latysheva AS, Zolottsev VA, Pokrovsky VS, Khan II, Misharin AY. Novel Nitrogen Containing Steroid Derivatives for Prostate Cancer Treatment. Curr Med Chem. 2021;28(40):8416-8432

Plyasova AA, Berrino E, Khan II, Veselovsky AV, Pokrovsky VS, Angeli A, Ferraroni M, Supuran CT, Pokrovskaya MV, Alexandrova SS, Gladilina YA, Sokolov NN, Hilal A, Carta F, Zhdanov DD. Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors. J Med Chem. 2021 Aug 12;64(15):11432-11444

Machulkin AE, Uspenskaya AA, Zyk NU, Nimenko EA, Ber AP, Petrov SA, Polshakov VI, Shafikov RR, Skvortsov DA, Plotnikova EA, Pankratov AA, Smirnova GB, Borisova YA, Pokrovsky VS, Kolmogorov VS, Vaneev AN, Khudyakov AD, Chepikova OE, Kovalev S, Zamyatnin AA Jr, Erofeev A, Gorelkin P, Beloglazkina EK, Zyk NV, Khazanova ES, Majouga AG. Synthesis, Characterization, and Preclinical Evaluation of a Small-Molecule Prostate-Specific Membrane Antigen-Targeted Monomethyl Auristatin E Conjugate. J Med Chem. 2021 Dec 9;64(23):17123-17145

Machulkin AE, Shafikov RR, Uspenskaya AA, Petrov SA, Ber AP, Skvortsov DA, Nimenko EA, Zyk NU, Smirnova GB, Pokrovsky VS, Abakumov MA, Saltykova IV, Akhmirov RT, Garanina AS, Polshakov VI, Saveliev OY, Ivanenkov YA, Aladinskaya AV, Finko AV, Yamansarov EU, Krasnovskaya OO, Erofeev AS, Gorelkin PV, Dontsova OA, Beloglazkina EK, Zyk NV, Khazanova ES, Majouga AG. Synthesis and Biological Evaluation of PSMA Ligands with Aromatic Residues and Fluorescent Conjugates Based on Them. J Med Chem. 2021 Apr 22;64(8):4532-4552

Lukasheva EV, Babayeva G, Karshieva SS, Zhdanov DD, Pokrovsky VS. L-Lysine α-Oxidase: Enzyme with Anticancer Properties. Pharmaceuticals (Basel). 2021 Oct 22;14(11):1070

Upadhyay N, Tilekar K, Hess JD, Pokrovsky VS, Aguilera RJ, Ramaa CS. Benefits and pitfalls: Epigenetic modulators in prostate cancer intervention. Current Research in Chemical Biology, 2021, 1, 100006

Tilekar K, Upadhyay N, Iancu CV, Pokrovsky V, Choe JY, Ramaa CS. Power of two: combination of therapeutic approaches involving glucose transporter (GLUT) inhibitors to combat cancer. Biochim Biophys Acta Rev Cancer. 2020 Dec;1874(2):188457

Latysheva AS, Zolottsev VA, Veselovsky AV, Scherbakov KA, Morozevich GE, Pokrovsky VS, Novikov RA, Timofeev VP, Tkachev YV, Misharin AY. New steroidal oxazolines, benzoxazoles and benzimidazoles related to abiraterone and galeterone. Steroids. 2020 Jan;153:108534

Zhdanov DD, Plyasova AA, Pokrovsky VS, Pokrovskaya MV, Alexandrova SS, Gladilina YA, Sokolov NN. Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes. Biochimie. 2020 Jul;174:34-43

Krasnovskaya OO, Guk DA, Naumov AE, Nikitina VN, Semkina AS, Vlasova KY, Pokrovsky V, Ryabaya OO, Karshieva SS, Skvortsov DA, Zhirkina IV, Shafikov RR, Gorelkin PV, Vaneev AN, Erofeev AS, Mazur DM, Tafeenko VA, Pergushov VI, Melnikov MY, Soldatov MA, Shapovalov VV, Soldatov AV, Akasov RA, Gerasimov VM, Sakharov DA, Moiseeva AA, Zyk NV, Beloglazkina EK, Majouga AG. Novel Copper-Containing Cytotoxic Agents Based on 2-Thioxoimidazolones. J Med Chem. 2020 Nov 12;63(21):13031-13063

Tilekar K, Upadhyay N, Meyer-Almes FJ, Loiodice F, Anisimova NY, Spirina TS, Sokolova DV, Smirnova GB, Choe JY, Pokrovsky VS, Lavecchia A, Ramaa C.S. Synthesis and Biological Evaluation of Pyrazoline and Pyrrolidine-2,5-dione Hybrids as Potential Antitumor Agents. ChemMedChem. 2020 Oct 5;15(19):1813-1825

Plyasova AA, Pokrovskaya MV, Lisitsyna OM, Pokrovsky VS, Alexandrova SS, Hilal A, Sokolov NN, Zhdanov DD. Penetration into Cancer Cells via Clathrin-Dependent Mechanism Allows L-Asparaginase from Rhodospirillum rubrum to Inhibit Telomerase. Pharmaceuticals (Basel). 2020 Sep 30;13(10):286

Pokrovsky VS, Zolottsev VA, Latysheva AS, Kudinov VA, Anisimova NY, Almanza RLM, Alekseeva OY, Baskaev KK, Smirnova GB, Borisova YA, Ipatova OM. Alsevirone-NF Reduces Serum Testosterone and Inhibits Prostate Cancer Xenograft Growth in Balb/c Nude Mice. Clinical Cancer Drugs, 2020, 7(2), 113-118

Pokrovsky VS, Yu Anisimova N, Zh Davydov D, Bazhenov SV, Bulushova NV, Zavilgelsky GB, Kotova VY, Manukhov IV. Methionine gamma lyase from Clostridium sporogenes increases the anticancer effect of doxorubicin in A549 cells and human cancer xenografts. Invest New Drugs. 2019 Apr;37(2):201-209

Zhdanov DD, Plyasova AA, Gladilina YA, Pokrovsky VS, Grishin DV, Grachev VA, Orlova VS, Pokrovskaya MV, Alexandrova SS, Lobaeva TA, Sokolov NN. Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes. Biochem Biophys Res Commun. 2019 Feb 12;509(3):790-796

Zhdanov DD, Gladilina YA, Pokrovsky VS, Grishin DV, Grachev VA, Orlova VS, Pokrovskaya MV, Alexandrova SS, Plyasova AA, Sokolov NN. Endonuclease G modulates the alternative splicing of deoxyribonuclease 1 mRNA in human CD4+ T lymphocytes and prevents the progression of apoptosis. Biochimie. 2019 Feb;157:158-176

Pokrovsky VS, Chepikova OE, Davydov DZ, Zamyatnin AA Jr, Lukashev AN, Lukasheva EV. Amino Acid Degrading Enzymes and their Application in Cancer Therapy. Curr Med Chem. 2019;26(3):446-464

Pokrovsky VS, Vinnikov D. Defining the toxicity of current regimens for extranodal NK/T cell lymphoma: a systematic review and metaproportion. Expert Rev Anticancer Ther. 2019 Jan;19(1):93-104

Pokrovsky VS, Anisimova NY, Davydov DZ, Bazhenov SV, Bulushova NV, Zavilgelsky GB, Kotova VY, Manukhov IV. Methionine Gamma Lyase from Clostridium sporogenes Increases the Anticancer Efficacy of Doxorubicin on A549 Cancer Cells In Vitro and Human Cancer Xenografts. Methods Mol Biol. 2019;1866:243-261

Kaidarova DR, Kopp MV, Pokrovsky VS, Dzhugashvili M, Akimzhanova ZM, Abdrakhmanov RZ, Babich EN, Bilan EV, Byakhov AV, Gurov SN, Koroleva IA, Mochalova AS, Povaga SS, Raigorodsky MV, Saifullin AS, Sanz E, Petrovskiy FI. Multicomponent nutritional supplement Oncoxin and its influence on quality of life and therapy toxicity in patients receiving adjuvant chemotherapy. Oncol Lett. 2019 Nov;18(5):5644-5652

Zhdanov DD, Gladilina YA, Pokrovsky VS, Grishin DV, Pokrovskaya MV, Aleksandrova SS, Plyasova AA, Sokolov NN. Prevention of apoptosis progression by Deoxyribonuclease I inactivation through Endonuclease G-induced alternative splicing of its mRNA. Cell Death Discovery, 2019, 5, 59-59

Pokrovskaya MV, Aleksandrova SS, Veselovsky AV, Zdanov DD, Pokrovsky VS, Eldarov MA, Grishin DV, Gladilina YA, Toropigin IY, Sokolov NN. Physical-Chemical Properties of L-asparaginase Mutants from Rhodospirillum Rubrum which Showed Antitelomerase Activity. Biomedical Chemistry: Research and Methods, 2019, 2(1), e00071-e00071

Zhdanov DD, Gladilina YA, Grishin DV, Grachev VA, Orlova VS, Pokrovskaya MV, Alexandrova SS, Pokrovsky VS, Sokolov NN. Contact-independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis. Mol Immunol. 2018 Sep;101:229-244

Zhdanov DD, Gladilina YA, Pokrovsky VS, Grishin DV, Grachev VA, Orlova VS, Pokrovskaya MV, Alexandrova SS, Sokolov NN. Murine regulatory T cells induce death of effector T, B, and NK lymphocytes through a contact-independent mechanism involving telomerase suppression and telomere-associated senescence. Cell Immunol. 2018 Sep;331:146-160

Grishin DV, Zhdanov DD, Gladilina JA, Pokrovsky VS, Podobed OV, Pokrovskaya MV, Aleksandrova SS, Milyushkina AL, Vigovskiy MA, Sokolov NN. Construction and characterization of a recombinant mutant homolog of the CheW protein from Thermotoga petrophila RKU-1. Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry, 2018, 12, 143-150

Zhdanov DD, Pokrovsky VS, Pokrovskaya MV, Alexandrova SS, Eldarov MA, Grishin DV, Basharov MM, Gladilina YA, Podobed OV, Sokolov NN. Rhodospirillum rubruml-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition. Biochem Biophys Res Commun. 2017 Oct 14;492(2):282-288

Morozova EA, Anufrieva NV, Davydov DZ, Komarova MV, Dyakov IN, Rodionov AN, Demidkina TV, Pokrovsky VS. Plasma methionine depletion and pharmacokinetic properties in mice of methionine γ-lyase from Citrobacter freundii, Clostridium tetani and Clostridium sporogenes. Biomedicine & Pharmacotherapy, 2017, 88, 978-984

Pokrovsky VS, Vinnikov D. L-Asparaginase for newly diagnosed extra-nodal NK/T-cell lymphoma: systematic review and meta-analysis. Expert Rev Anticancer Ther. 2017 Aug;17(8):759-768

Zhdanov DD, Pokrovsky VS, Pokrovskaya MV, Alexandrova SS, Eldarov MA, Grishin DV, Basharov MM, Gladilina YA, Podobed OV, Sokolov NN. Inhibition of telomerase activity and induction of apoptosis by Rhodospirillum rubrum L-asparaginase in cancer Jurkat cell line and normal human CD4+ T lymphocytes. Cancer Med. 2017 Nov;6(11):2697-2712

Pechkova E, Fiordoro S, Sokolov N, Pokrovsky V, Pokrovskaya M, Aleksandrova S, Veselovsky A, Bragazzi N, Giannini M, Yi SZ, Eldarov M, Martelli PL, Zanotti G, Nicolini C. LB crystallization and preliminary X-ray diffraction analysis of L-Asparaginase from Rhodospirillum rubrum. NanoWorld J, 2017, 3(S1), S2-S8

Sannikova EP, Bulushova NV, Cheperegin SE, Gubaydullin II, Chestukhina GG, Ryabichenko VV, Zalunin IA, Kotlova EK, Konstantinova GE, Kubasova TS, Shtil AA, Pokrovsky VS, Yarotsky SV, Efremov BD, Kozlov DG. The Modified Heparin-Binding L-Asparaginase of Wolinella succinogenes. Mol Biotechnol. 2016 Sep;58(8-9):528-39

Pokrovsky VS, Kazanov MD, Dyakov IN, Pokrovskaya MV, Aleksandrova SS. Comparative immunogenicity and structural analysis of epitopes of different bacterial L-asparaginases. BMC Cancer. 2016 Feb 11;16:89

Pokrovskaya MV, Aleksandrova SS, Pokrovsky VS, Veselovsky AV, Grishin DV, Abakumova OY, Podobed OV, Mishin AA, Zhdanov DD, Sokolov NN. Identification of functional regions in the Rhodospirillum rubrum L-asparaginase by site-directed mutagenesis. Mol Biotechnol. 2015 Mar;57(3):251-64

Pokrovsky VS, Treshalina HM, Lukasheva EV, Sedakova LA, Medentzev AG, Arinbasarova AY, Berezov TT. Enzymatic properties and anticancer activity of L-lysine α-oxidase from Trichoderma cf. aureoviride Rifai BKMF-4268D. Anticancer Drugs. 2013 Sep;24(8):846-51

Babich OO, Pokrovsky VS, Anisimova NY, Sokolov NN, Prosekov AY. Recombinant l-phenylalanine ammonia lyase from Rhodosporidium toruloides as a potential anticancer agent. Biotechnol Appl Biochem. 2013 May-Jun;60(3):316-22

Savitsky AP, Meerovich IG, Zherdeva VV, Arslanbaeva LR, Burova OS, Sokolova DV, Treshchalina EM, Baryshnikov AY, Fiks II, Orlova AG, Kleshnin MS, Turchin IV, Sergeev AM. Three-dimensional in vivo imaging of tumors expressing red fluorescent proteins. Methods Mol Biol. 2012;872:97-114